DNAJB6 Myopathies: Focused Review on an Emerging and Expanding Group of Myopathies
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چکیده
منابع مشابه
DNAJB6 Myopathies: Focused Review on an Emerging and Expanding Group of Myopathies
Mutations in the DNAJB6 gene have been associated with the autosomal dominant limb girdle muscular dystrophy type 1D (LGMD1D), a disorder characterized by abnormal protein aggregates and rimmed vacuoles in muscle fibers. DNAJB6 is a ubiquitously expressed Hsp40 co-chaperone characterized by a J domain that specifies Hsp70 functions in the cellular environment. DNAJB6 is also a potent inhibitor ...
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ژورنال
عنوان ژورنال: Frontiers in Molecular Biosciences
سال: 2016
ISSN: 2296-889X
DOI: 10.3389/fmolb.2016.00063